Scintigraphic methods to detect β2‐microglobulin associated amyloidosis (Aβ2‐microglobulin amyloidosis)

Amyloidosis-associated kidney disease.

The amyloidoses are a group of disorders in which soluble proteins aggregate and deposit extracellularly in tissues as insoluble fibrils, causing progressive organ dysfunction. The kidney is one of the most frequent sites of amyloid deposition in AL, AA, and several of the hereditary amyloidoses. Amyloid fibril formation begins with the misfolding of an amyloidogenic precursor protein. The misf...

Isolated Laryngeal Amyloidosis

Amyloidosis - Pathogenesis | Systemic amyloidosis | Pharmacybook

Immunoglobulin heavy-chain-associated amyloidosis.

Immunoglobulin- or multiple myeloma-associated amyloidosis has been distinguished by the tissue deposition of Congophilic, fibrillar protein consisting of light chains or light-chain fragments (AL amyloidosis). We now report the isolation and characterization of another form of immunoglobulin-associated amyloid obtained from a patient who had extensive systemic amyloidosis and in whom the amylo...

Amyloidosis - Pathogenesis | Systemic amyloidosis | Pharmacybook